Page 19 - Periodic Issue 04
P. 19

A Unique Oxford


                                                       Experience: the Chemistry

                                                       Part II



                                                       The Part II, which has had a very similar format for the past 100 years,
             (in unison) was ’research please’.  Prof   is very much the jewel in the crown of the Oxford Chemistry course.
             pointedly asked who on earth would        It gives students a unique opportunity to carry out original research,
             have us?  The answer was that Geoffrey    enabling them to apply the knowledge and understanding they have
             Young and Dr William Waters were          gained over the preceding three years.  Part II students choose their
             prepared to take us on.                   research project from a wide range of fields – from theoretical and
                                                       computational chemistry to organic synthesis – and spend a whole year
             ‘Well, I do not wish to see you again so   working on a cutting-edge project with world-leading researchers.
             you both better get on with it’ was the
             response.  Years later I was amazed to    The Part II offers an invaluable opportunity to sample life as a
             find at the RSC (where I was pleased to   professional chemist and to develop initiative and critical thinking
             have been voted a fellow) the portraits   skills.  Part II research projects have led to the publication of a great
             of HR Perkins and Sir Ewart hanging       many articles in the scientific literature, and even to significant
             side by side, smiling at me.              advances in our understanding of many areas of chemistry.


             Throughout the next two years,
             whenever the class was practical
             organic, Terry and I ‘assisted’ in the labs
             and made many friends in the research
             groups we joined. Bruce Merryfield
             played a key part in my life because of
             his development of solid phase peptide
             synthesis which led to a lifelong interest
             in affinity chromatography and the
             phenyl boronate based HbA1c test that
             every diabetic knows well.  I did my
             part II with T G Halsall – this ended
             up as a synthetic project with Michael
             Whitehouse and the invention of a new
             method to hydrolyse hindered methyl       Margaret Thatcher (1925-2013), British Prime Minister from 1979
             esters with lithium iodide and DMF.       to 1990, completed her Part II under the supervision of Nobel Laureate
             I made 4-5 grams of diazomethane          Dorothy Hodgkin and worked as an industrial chemist before entering
             at 3 o’clock in the morning with no–      politics.
             one else in the building.  My sister
             could have foreseen what might have
             happened but the fact that quality
             teaching will out meant that all went        How did your Part II shape your career?
             well.
                                                          It is almost one hundred years since the first Part II thesis
             If it had not been for the DP, I would       was completed in 1917, and we would love to hear your
             not have worked with the Biochemistry        stories and recollections of how this unique experience
             Department, nor done a post-doc with         shaped your future.  Please get in touch with Susan Davis,
             Corey and Bloch, nor would I have I          Alumni Relations and Communications Officer, Depart-
             have helped the 400 million diabetics        ment of Chemistry, Physical and Theoretical Chemistry
             in the world live more easily with their     Laboratory, South Parks Road, Oxford OX1 3QZ, or
             condition and neither would I now
             have an Oxford DSc!                          email alumni@chem.ox.ac.uk.  We will publish a selection
                                                          of your stories in the next edition of Periodic.  Thank you!



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                                                                                                    Periodic
                                                               The Magazine of the Department of Chemistry
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